Music Exposure Induced Prolongation of Cardiac Allograft Survival and Generated Regulatory CD4+ Cells in Mice
Identifieur interne :
000043 ( PascalFrancis/Corpus );
précédent :
000042;
suivant :
000044
Music Exposure Induced Prolongation of Cardiac Allograft Survival and Generated Regulatory CD4+ Cells in Mice
Auteurs : M. Uchiyama ;
X. Jin ;
Q. Zhang ;
A. Amano ;
T. Watanabe ;
M. NiimiSource :
-
Transplantation proceedings [ 0041-1345 ] ; 2012.
RBID : Pascal:12-0238595
Descripteurs français
- Pascal (Inist)
- Homotransplantation,
Musique,
Exposition,
Coeur,
Survie,
Pronostic,
Lymphocyte T,
Animal,
Souris,
Médecine,
Transplantation,
Greffe,
Traitement,
Antigène CD4,
Cellule régulatrice.
English descriptors
- KwdEn :
- Animal,
Exposure,
Graft,
Heart,
Homotransplantation,
Medicine,
Mouse,
Music,
Prognosis,
Regulatory cell,
Survival,
T-Lymphocyte,
Transplantation,
Treatment.
Abstract
In clinical practice, music has been used to decrease stress, heart rate, and blood pressure and to provide a distraction from disease symptoms. We investigated sound effects on alloimmune responses in murine heart transplantation. Naive and eardrum-ruptured CBA/N (CBA, H2K) underwent transplantation of a C57BL/6 (B6, H2b) heart and were exposed to 1 of 3 types of music-opera (La Traviata), classical (Mozart), and New Age (Enya)-or 1 of 6 different single sound frequencies for 7 days. An adoptive transfer study was performed to determine whether regulatory cells were generated in allograft recipients. Cell-proliferation, cytokine, and flow cytometry assessments were also performed. CBA recipients of a B6 graft exposed to opera and classical music had significantly prolonged allograft survival (median survival times [MSTs], 26.5 and 20 days, respectively), whereas those exposed to 6 single sound frequencies and New Age did not (MSTs, 7, 8, 9, 8, 8, 8, and 11 days, respectively). Untreated and eardrum-ruptured CBA rejected B6 grafts acutely (MSTs, 7 and 8.5 days, respectively). Adoptive transfer of whole splenocytes, CD4+ cells, and CD4+CD25+ cells from opera-exposed primary recipients resulted in significantly prolonged allograft survival in naive secondary recipients (MSTs, 36, 68, and >50 days, respectively). Cell-proliferation, interleukin (IL)-2 and interferon-y were suppressed in opera-exposed mice, whereas IL-4 and IL-10 from opera-exposed recipients were up-regulated. Flow cytometry studies showed an increased CD4+CD25+Foxp3+ cell population in splenocytes from opera-exposed mice. In conclusion, exposure to some types of music may induce prolonged survival of fully allogeneic cardiac allografts and generate CD4+CD25+Foxp3+ regulatory cells.
Notice en format standard (ISO 2709)
Pour connaître la documentation sur le format Inist Standard.
| pA |
| A01 | 01 | 1 | | @0 0041-1345 |
|---|
| A02 | 01 | | | @0 TRPPA8 |
|---|
| A03 | | 1 | | @0 Transplant. proc. |
|---|
| A05 | | | | @2 44 |
|---|
| A06 | | | | @2 4 |
|---|
| A08 | 01 | 1 | ENG | @1 Music Exposure Induced Prolongation of Cardiac Allograft Survival and Generated Regulatory CD4+ Cells in Mice |
|---|
| A09 | 01 | 1 | ENG | @1 CAST 2011: Proceedings of the 12th Congress of the Asian Society of Transplantation, September 25-28, 2011, Seoul, Korea - Other Clinical and Investigative Arenas in Transplantation |
|---|
| A11 | 01 | 1 | | @1 UCHIYAMA (M.) |
|---|
| A11 | 02 | 1 | | @1 JIN (X.) |
|---|
| A11 | 03 | 1 | | @1 ZHANG (Q.) |
|---|
| A11 | 04 | 1 | | @1 AMANO (A.) |
|---|
| A11 | 05 | 1 | | @1 WATANABE (T.) |
|---|
| A11 | 06 | 1 | | @1 NIIMI (M.) |
|---|
| A12 | 01 | 1 | | @1 YU SEUN KIM @9 ed. |
|---|
| A12 | 02 | 1 | | @1 SU KIL PARK @9 ed. |
|---|
| A14 | 01 | | | @1 Department of Cardiovascular Surgery , Juntendo University Hospital @2 Tokyo @3 JPN @Z 1 aut. @Z 4 aut. |
|---|
| A14 | 02 | | | @1 Department of Surgery , Teikyo University @2 Tokyo @3 JPN @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 5 aut. @Z 6 aut. |
|---|
| A14 | 03 | | | @1 Department of Cardiovascular and Thoracic Surgery , The 4th Affiliated Hospital to Harbin Medical University @2 Harbin @3 CHN @Z 2 aut. |
|---|
| A18 | 01 | 1 | | @1 Asian Society of Transplantation (AST) @3 INC @9 org-cong. |
|---|
| A20 | | | | @1 1076-1079 |
|---|
| A21 | | | | @1 2012 |
|---|
| A23 | 01 | | | @0 ENG |
|---|
| A43 | 01 | | | @1 INIST @2 14765 @5 354000506991730710 |
|---|
| A44 | | | | @0 0000 @1 © 2012 INIST-CNRS. All rights reserved. |
|---|
| A45 | | | | @0 16 ref. |
|---|
| A47 | 01 | 1 | | @0 12-0238595 |
|---|
| A60 | | | | @1 P @2 C |
|---|
| A61 | | | | @0 A |
|---|
| A64 | 01 | 1 | | @0 Transplantation proceedings |
|---|
| A66 | 01 | | | @0 NLD |
|---|
| C01 | 01 | | ENG | @0 In clinical practice, music has been used to decrease stress, heart rate, and blood pressure and to provide a distraction from disease symptoms. We investigated sound effects on alloimmune responses in murine heart transplantation. Naive and eardrum-ruptured CBA/N (CBA, H2K) underwent transplantation of a C57BL/6 (B6, H2b) heart and were exposed to 1 of 3 types of music-opera (La Traviata), classical (Mozart), and New Age (Enya)-or 1 of 6 different single sound frequencies for 7 days. An adoptive transfer study was performed to determine whether regulatory cells were generated in allograft recipients. Cell-proliferation, cytokine, and flow cytometry assessments were also performed. CBA recipients of a B6 graft exposed to opera and classical music had significantly prolonged allograft survival (median survival times [MSTs], 26.5 and 20 days, respectively), whereas those exposed to 6 single sound frequencies and New Age did not (MSTs, 7, 8, 9, 8, 8, 8, and 11 days, respectively). Untreated and eardrum-ruptured CBA rejected B6 grafts acutely (MSTs, 7 and 8.5 days, respectively). Adoptive transfer of whole splenocytes, CD4+ cells, and CD4+CD25+ cells from opera-exposed primary recipients resulted in significantly prolonged allograft survival in naive secondary recipients (MSTs, 36, 68, and >50 days, respectively). Cell-proliferation, interleukin (IL)-2 and interferon-y were suppressed in opera-exposed mice, whereas IL-4 and IL-10 from opera-exposed recipients were up-regulated. Flow cytometry studies showed an increased CD4+CD25+Foxp3+ cell population in splenocytes from opera-exposed mice. In conclusion, exposure to some types of music may induce prolonged survival of fully allogeneic cardiac allografts and generate CD4+CD25+Foxp3+ regulatory cells. |
|---|
| C02 | 01 | X | | @0 002B25 |
|---|
| C02 | 02 | X | | @0 002A06F |
|---|
| C03 | 01 | X | FRE | @0 Homotransplantation @5 01 |
|---|
| C03 | 01 | X | ENG | @0 Homotransplantation @5 01 |
|---|
| C03 | 01 | X | SPA | @0 Homotrasplante @5 01 |
|---|
| C03 | 02 | X | FRE | @0 Musique @5 02 |
|---|
| C03 | 02 | X | ENG | @0 Music @5 02 |
|---|
| C03 | 02 | X | SPA | @0 Música @5 02 |
|---|
| C03 | 03 | X | FRE | @0 Exposition @5 03 |
|---|
| C03 | 03 | X | ENG | @0 Exposure @5 03 |
|---|
| C03 | 03 | X | SPA | @0 Exposición @5 03 |
|---|
| C03 | 04 | X | FRE | @0 Coeur @5 05 |
|---|
| C03 | 04 | X | ENG | @0 Heart @5 05 |
|---|
| C03 | 04 | X | SPA | @0 Corazón @5 05 |
|---|
| C03 | 05 | X | FRE | @0 Survie @5 06 |
|---|
| C03 | 05 | X | ENG | @0 Survival @5 06 |
|---|
| C03 | 05 | X | SPA | @0 Sobrevivencia @5 06 |
|---|
| C03 | 06 | X | FRE | @0 Pronostic @5 08 |
|---|
| C03 | 06 | X | ENG | @0 Prognosis @5 08 |
|---|
| C03 | 06 | X | SPA | @0 Pronóstico @5 08 |
|---|
| C03 | 07 | X | FRE | @0 Lymphocyte T @5 09 |
|---|
| C03 | 07 | X | ENG | @0 T-Lymphocyte @5 09 |
|---|
| C03 | 07 | X | SPA | @0 Linfocito T @5 09 |
|---|
| C03 | 08 | X | FRE | @0 Animal @5 11 |
|---|
| C03 | 08 | X | ENG | @0 Animal @5 11 |
|---|
| C03 | 08 | X | SPA | @0 Animal @5 11 |
|---|
| C03 | 09 | X | FRE | @0 Souris @5 12 |
|---|
| C03 | 09 | X | ENG | @0 Mouse @5 12 |
|---|
| C03 | 09 | X | SPA | @0 Ratón @5 12 |
|---|
| C03 | 10 | X | FRE | @0 Médecine @5 17 |
|---|
| C03 | 10 | X | ENG | @0 Medicine @5 17 |
|---|
| C03 | 10 | X | SPA | @0 Medicina @5 17 |
|---|
| C03 | 11 | X | FRE | @0 Transplantation @5 18 |
|---|
| C03 | 11 | X | ENG | @0 Transplantation @5 18 |
|---|
| C03 | 11 | X | SPA | @0 Trasplantación @5 18 |
|---|
| C03 | 12 | X | FRE | @0 Greffe @5 25 |
|---|
| C03 | 12 | X | ENG | @0 Graft @5 25 |
|---|
| C03 | 12 | X | SPA | @0 Injerto @5 25 |
|---|
| C03 | 13 | X | FRE | @0 Traitement @5 26 |
|---|
| C03 | 13 | X | ENG | @0 Treatment @5 26 |
|---|
| C03 | 13 | X | SPA | @0 Tratamiento @5 26 |
|---|
| C03 | 14 | X | FRE | @0 Antigène CD4 @4 INC @5 86 |
|---|
| C03 | 15 | X | FRE | @0 Cellule régulatrice @4 CD @5 96 |
|---|
| C03 | 15 | X | ENG | @0 Regulatory cell @4 CD @5 96 |
|---|
| C07 | 01 | X | FRE | @0 Rodentia @2 NS |
|---|
| C07 | 01 | X | ENG | @0 Rodentia @2 NS |
|---|
| C07 | 01 | X | SPA | @0 Rodentia @2 NS |
|---|
| C07 | 02 | X | FRE | @0 Mammalia @2 NS |
|---|
| C07 | 02 | X | ENG | @0 Mammalia @2 NS |
|---|
| C07 | 02 | X | SPA | @0 Mammalia @2 NS |
|---|
| C07 | 03 | X | FRE | @0 Vertebrata @2 NS |
|---|
| C07 | 03 | X | ENG | @0 Vertebrata @2 NS |
|---|
| C07 | 03 | X | SPA | @0 Vertebrata @2 NS |
|---|
| C07 | 04 | X | FRE | @0 Chirurgie @5 37 |
|---|
| C07 | 04 | X | ENG | @0 Surgery @5 37 |
|---|
| C07 | 04 | X | SPA | @0 Cirugía @5 37 |
|---|
| C07 | 05 | X | FRE | @0 Appareil circulatoire @5 38 |
|---|
| C07 | 05 | X | ENG | @0 Circulatory system @5 38 |
|---|
| C07 | 05 | X | SPA | @0 Aparato circulatorio @5 38 |
|---|
| N21 | | | | @1 184 |
|---|
| N44 | 01 | | | @1 OTO |
|---|
| N82 | | | | @1 OTO |
|---|
|
|---|
| pR |
| A30 | 01 | 1 | ENG | @1 Congress of the Asian Society of Transplantation @2 12 @3 Seoul KOR @4 2011-09-25 |
|---|
|
|---|
Format Inist (serveur)
| NO : | PASCAL 12-0238595 INIST |
|---|
| ET : | Music Exposure Induced Prolongation of Cardiac Allograft Survival and Generated Regulatory CD4+ Cells in Mice |
|---|
| AU : | UCHIYAMA (M.); JIN (X.); ZHANG (Q.); AMANO (A.); WATANABE (T.); NIIMI (M.); YU SEUN KIM; SU KIL PARK |
|---|
| AF : | Department of Cardiovascular Surgery , Juntendo University Hospital/Tokyo/Japon (1 aut., 4 aut.); Department of Surgery , Teikyo University/Tokyo/Japon (1 aut., 2 aut., 3 aut., 5 aut., 6 aut.); Department of Cardiovascular and Thoracic Surgery , The 4th Affiliated Hospital to Harbin Medical University/Harbin/Chine (2 aut.) |
|---|
| DT : | Publication en série; Congrès; Niveau analytique |
|---|
| SO : | Transplantation proceedings; ISSN 0041-1345; Coden TRPPA8; Pays-Bas; Da. 2012; Vol. 44; No. 4; Pp. 1076-1079; Bibl. 16 ref. |
|---|
| LA : | Anglais |
|---|
| EA : | In clinical practice, music has been used to decrease stress, heart rate, and blood pressure and to provide a distraction from disease symptoms. We investigated sound effects on alloimmune responses in murine heart transplantation. Naive and eardrum-ruptured CBA/N (CBA, H2K) underwent transplantation of a C57BL/6 (B6, H2b) heart and were exposed to 1 of 3 types of music-opera (La Traviata), classical (Mozart), and New Age (Enya)-or 1 of 6 different single sound frequencies for 7 days. An adoptive transfer study was performed to determine whether regulatory cells were generated in allograft recipients. Cell-proliferation, cytokine, and flow cytometry assessments were also performed. CBA recipients of a B6 graft exposed to opera and classical music had significantly prolonged allograft survival (median survival times [MSTs], 26.5 and 20 days, respectively), whereas those exposed to 6 single sound frequencies and New Age did not (MSTs, 7, 8, 9, 8, 8, 8, and 11 days, respectively). Untreated and eardrum-ruptured CBA rejected B6 grafts acutely (MSTs, 7 and 8.5 days, respectively). Adoptive transfer of whole splenocytes, CD4+ cells, and CD4+CD25+ cells from opera-exposed primary recipients resulted in significantly prolonged allograft survival in naive secondary recipients (MSTs, 36, 68, and >50 days, respectively). Cell-proliferation, interleukin (IL)-2 and interferon-y were suppressed in opera-exposed mice, whereas IL-4 and IL-10 from opera-exposed recipients were up-regulated. Flow cytometry studies showed an increased CD4+CD25+Foxp3+ cell population in splenocytes from opera-exposed mice. In conclusion, exposure to some types of music may induce prolonged survival of fully allogeneic cardiac allografts and generate CD4+CD25+Foxp3+ regulatory cells. |
|---|
| CC : | 002B25; 002A06F |
|---|
| FD : | Homotransplantation; Musique; Exposition; Coeur; Survie; Pronostic; Lymphocyte T; Animal; Souris; Médecine; Transplantation; Greffe; Traitement; Antigène CD4; Cellule régulatrice |
|---|
| FG : | Rodentia; Mammalia; Vertebrata; Chirurgie; Appareil circulatoire |
|---|
| ED : | Homotransplantation; Music; Exposure; Heart; Survival; Prognosis; T-Lymphocyte; Animal; Mouse; Medicine; Transplantation; Graft; Treatment; Regulatory cell |
|---|
| EG : | Rodentia; Mammalia; Vertebrata; Surgery; Circulatory system |
|---|
| SD : | Homotrasplante; Música; Exposición; Corazón; Sobrevivencia; Pronóstico; Linfocito T; Animal; Ratón; Medicina; Trasplantación; Injerto; Tratamiento |
|---|
| LO : | INIST-14765.354000506991730710 |
|---|
| ID : | 12-0238595 |
|---|
Links to Exploration step
Pascal:12-0238595
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Music Exposure Induced Prolongation of Cardiac Allograft Survival and Generated Regulatory CD4<sup>+</sup>
Cells in Mice</title><author><name sortKey="Uchiyama, M" sort="Uchiyama, M" uniqKey="Uchiyama M" first="M." last="Uchiyama">M. Uchiyama</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Cardiovascular Surgery , Juntendo University Hospital</s1>
<s2>Tokyo</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14><affiliation><inist:fA14 i1="02"><s1>Department of Surgery , Teikyo University</s1>
<s2>Tokyo</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14><author><name sortKey="Jin, X" sort="Jin, X" uniqKey="Jin X" first="X." last="Jin">X. Jin</name>
<affiliation><inist:fA14 i1="02"><s1>Department of Surgery , Teikyo University</s1>
<s2>Tokyo</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14><affiliation><inist:fA14 i1="03"><s1>Department of Cardiovascular and Thoracic Surgery , The 4th Affiliated Hospital to Harbin Medical University</s1>
<s2>Harbin</s2>
<s3>CHN</s3>
<sZ>2 aut.</sZ>
</inist:fA14><author><name sortKey="Zhang, Q" sort="Zhang, Q" uniqKey="Zhang Q" first="Q." last="Zhang">Q. Zhang</name>
<affiliation><inist:fA14 i1="02"><s1>Department of Surgery , Teikyo University</s1>
<s2>Tokyo</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14><author><name sortKey="Amano, A" sort="Amano, A" uniqKey="Amano A" first="A." last="Amano">A. Amano</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Cardiovascular Surgery , Juntendo University Hospital</s1>
<s2>Tokyo</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14><author><name sortKey="Watanabe, T" sort="Watanabe, T" uniqKey="Watanabe T" first="T." last="Watanabe">T. Watanabe</name>
<affiliation><inist:fA14 i1="02"><s1>Department of Surgery , Teikyo University</s1>
<s2>Tokyo</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14><author><name sortKey="Niimi, M" sort="Niimi, M" uniqKey="Niimi M" first="M." last="Niimi">M. Niimi</name>
<affiliation><inist:fA14 i1="02"><s1>Department of Surgery , Teikyo University</s1>
<s2>Tokyo</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14><publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">12-0238595</idno>
<date when="2012">2012</date>
<idno type="stanalyst">PASCAL 12-0238595 INIST</idno>
<idno type="RBID">Pascal:12-0238595</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000043</idno>
</publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Music Exposure Induced Prolongation of Cardiac Allograft Survival and Generated Regulatory CD4<sup>+</sup>
Cells in Mice</title><author><name sortKey="Uchiyama, M" sort="Uchiyama, M" uniqKey="Uchiyama M" first="M." last="Uchiyama">M. Uchiyama</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Cardiovascular Surgery , Juntendo University Hospital</s1>
<s2>Tokyo</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14><affiliation><inist:fA14 i1="02"><s1>Department of Surgery , Teikyo University</s1>
<s2>Tokyo</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14><author><name sortKey="Jin, X" sort="Jin, X" uniqKey="Jin X" first="X." last="Jin">X. Jin</name>
<affiliation><inist:fA14 i1="02"><s1>Department of Surgery , Teikyo University</s1>
<s2>Tokyo</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14><affiliation><inist:fA14 i1="03"><s1>Department of Cardiovascular and Thoracic Surgery , The 4th Affiliated Hospital to Harbin Medical University</s1>
<s2>Harbin</s2>
<s3>CHN</s3>
<sZ>2 aut.</sZ>
</inist:fA14><author><name sortKey="Zhang, Q" sort="Zhang, Q" uniqKey="Zhang Q" first="Q." last="Zhang">Q. Zhang</name>
<affiliation><inist:fA14 i1="02"><s1>Department of Surgery , Teikyo University</s1>
<s2>Tokyo</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14><author><name sortKey="Amano, A" sort="Amano, A" uniqKey="Amano A" first="A." last="Amano">A. Amano</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Cardiovascular Surgery , Juntendo University Hospital</s1>
<s2>Tokyo</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14><author><name sortKey="Watanabe, T" sort="Watanabe, T" uniqKey="Watanabe T" first="T." last="Watanabe">T. Watanabe</name>
<affiliation><inist:fA14 i1="02"><s1>Department of Surgery , Teikyo University</s1>
<s2>Tokyo</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14><author><name sortKey="Niimi, M" sort="Niimi, M" uniqKey="Niimi M" first="M." last="Niimi">M. Niimi</name>
<affiliation><inist:fA14 i1="02"><s1>Department of Surgery , Teikyo University</s1>
<s2>Tokyo</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14><series><title level="j" type="main">Transplantation proceedings</title>
<title level="j" type="abbreviated">Transplant. proc.</title>
<idno type="ISSN">0041-1345</idno>
<imprint><date when="2012">2012</date>
</imprint><seriesStmt><title level="j" type="main">Transplantation proceedings</title>
<title level="j" type="abbreviated">Transplant. proc.</title>
<idno type="ISSN">0041-1345</idno>
</seriesStmt><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animal</term>
<term>Exposure</term>
<term>Graft</term>
<term>Heart</term>
<term>Homotransplantation</term>
<term>Medicine</term>
<term>Mouse</term>
<term>Music</term>
<term>Prognosis</term>
<term>Regulatory cell</term>
<term>Survival</term>
<term>T-Lymphocyte</term>
<term>Transplantation</term>
<term>Treatment</term>
</keywords><keywords scheme="Pascal" xml:lang="fr"><term>Homotransplantation</term>
<term>Musique</term>
<term>Exposition</term>
<term>Coeur</term>
<term>Survie</term>
<term>Pronostic</term>
<term>Lymphocyte T</term>
<term>Animal</term>
<term>Souris</term>
<term>Médecine</term>
<term>Transplantation</term>
<term>Greffe</term>
<term>Traitement</term>
<term>Antigène CD4</term>
<term>Cellule régulatrice</term>
</keywords><front><div type="abstract" xml:lang="en">In clinical practice, music has been used to decrease stress, heart rate, and blood pressure and to provide a distraction from disease symptoms. We investigated sound effects on alloimmune responses in murine heart transplantation. Naive and eardrum-ruptured CBA/N (CBA, H2<sup>K</sup>
) underwent transplantation of a C57BL/6 (B6, H2<sup>b</sup>
) heart and were exposed to 1 of 3 types of music-opera (La Traviata), classical (Mozart), and New Age (Enya)-or 1 of 6 different single sound frequencies for 7 days. An adoptive transfer study was performed to determine whether regulatory cells were generated in allograft recipients. Cell-proliferation, cytokine, and flow cytometry assessments were also performed. CBA recipients of a B6 graft exposed to opera and classical music had significantly prolonged allograft survival (median survival times [MSTs], 26.5 and 20 days, respectively), whereas those exposed to 6 single sound frequencies and New Age did not (MSTs, 7, 8, 9, 8, 8, 8, and 11 days, respectively). Untreated and eardrum-ruptured CBA rejected B6 grafts acutely (MSTs, 7 and 8.5 days, respectively). Adoptive transfer of whole splenocytes, CD4<sup>+</sup>
cells, and CD4<sup>+</sup>
CD25<sup>+</sup>
cells from opera-exposed primary recipients resulted in significantly prolonged allograft survival in naive secondary recipients (MSTs, 36, 68, and >50 days, respectively). Cell-proliferation, interleukin (IL)-2 and interferon-y were suppressed in opera-exposed mice, whereas IL-4 and IL-10 from opera-exposed recipients were up-regulated. Flow cytometry studies showed an increased CD4<sup>+</sup>
CD25<sup>+</sup>
Foxp3<sup>+</sup>
cell population in splenocytes from opera-exposed mice. In conclusion, exposure to some types of music may induce prolonged survival of fully allogeneic cardiac allografts and generate CD4<sup>+</sup>
CD25<sup>+</sup>
Foxp3<sup>+</sup>
regulatory cells.</div><inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0041-1345</s0>
</fA01><fA02 i1="01"><s0>TRPPA8</s0>
</fA02><fA03 i2="1"><s0>Transplant. proc.</s0>
</fA03><fA08 i1="01" i2="1" l="ENG"><s1>Music Exposure Induced Prolongation of Cardiac Allograft Survival and Generated Regulatory CD4<sup>+</sup>
Cells in Mice</s1><fA09 i1="01" i2="1" l="ENG"><s1>CAST 2011: Proceedings of the 12th Congress of the Asian Society of Transplantation, September 25-28, 2011, Seoul, Korea - Other Clinical and Investigative Arenas in Transplantation</s1>
</fA09><fA11 i1="01" i2="1"><s1>UCHIYAMA (M.)</s1>
</fA11><fA11 i1="02" i2="1"><s1>JIN (X.)</s1>
</fA11><fA11 i1="03" i2="1"><s1>ZHANG (Q.)</s1>
</fA11><fA11 i1="04" i2="1"><s1>AMANO (A.)</s1>
</fA11><fA11 i1="05" i2="1"><s1>WATANABE (T.)</s1>
</fA11><fA11 i1="06" i2="1"><s1>NIIMI (M.)</s1>
</fA11><fA12 i1="01" i2="1"><s1>YU SEUN KIM</s1>
<s9>ed.</s9>
</fA12><fA12 i1="02" i2="1"><s1>SU KIL PARK</s1>
<s9>ed.</s9>
</fA12><fA14 i1="01"><s1>Department of Cardiovascular Surgery , Juntendo University Hospital</s1>
<s2>Tokyo</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
</fA14><fA14 i1="02"><s1>Department of Surgery , Teikyo University</s1>
<s2>Tokyo</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</fA14><fA14 i1="03"><s1>Department of Cardiovascular and Thoracic Surgery , The 4th Affiliated Hospital to Harbin Medical University</s1>
<s2>Harbin</s2>
<s3>CHN</s3>
<sZ>2 aut.</sZ>
</fA14><fA18 i1="01" i2="1"><s1>Asian Society of Transplantation (AST)</s1>
<s3>INC</s3>
<s9>org-cong.</s9>
</fA18><fA20><s1>1076-1079</s1>
</fA20><fA21><s1>2012</s1>
</fA21><fA23 i1="01"><s0>ENG</s0>
</fA23><fA43 i1="01"><s1>INIST</s1>
<s2>14765</s2>
<s5>354000506991730710</s5>
</fA43><fA44><s0>0000</s0>
<s1>© 2012 INIST-CNRS. All rights reserved.</s1>
</fA44><fA45><s0>16 ref.</s0>
</fA45><fA47 i1="01" i2="1"><s0>12-0238595</s0>
</fA47><fA60><s1>P</s1>
<s2>C</s2>
</fA60><fA64 i1="01" i2="1"><s0>Transplantation proceedings</s0>
</fA64><fA66 i1="01"><s0>NLD</s0>
</fA66><fC01 i1="01" l="ENG"><s0>In clinical practice, music has been used to decrease stress, heart rate, and blood pressure and to provide a distraction from disease symptoms. We investigated sound effects on alloimmune responses in murine heart transplantation. Naive and eardrum-ruptured CBA/N (CBA, H2<sup>K</sup>
) underwent transplantation of a C57BL/6 (B6, H2<sup>b</sup>
) heart and were exposed to 1 of 3 types of music-opera (La Traviata), classical (Mozart), and New Age (Enya)-or 1 of 6 different single sound frequencies for 7 days. An adoptive transfer study was performed to determine whether regulatory cells were generated in allograft recipients. Cell-proliferation, cytokine, and flow cytometry assessments were also performed. CBA recipients of a B6 graft exposed to opera and classical music had significantly prolonged allograft survival (median survival times [MSTs], 26.5 and 20 days, respectively), whereas those exposed to 6 single sound frequencies and New Age did not (MSTs, 7, 8, 9, 8, 8, 8, and 11 days, respectively). Untreated and eardrum-ruptured CBA rejected B6 grafts acutely (MSTs, 7 and 8.5 days, respectively). Adoptive transfer of whole splenocytes, CD4<sup>+</sup>
cells, and CD4<sup>+</sup>
CD25<sup>+</sup>
cells from opera-exposed primary recipients resulted in significantly prolonged allograft survival in naive secondary recipients (MSTs, 36, 68, and >50 days, respectively). Cell-proliferation, interleukin (IL)-2 and interferon-y were suppressed in opera-exposed mice, whereas IL-4 and IL-10 from opera-exposed recipients were up-regulated. Flow cytometry studies showed an increased CD4<sup>+</sup>
CD25<sup>+</sup>
Foxp3<sup>+</sup>
cell population in splenocytes from opera-exposed mice. In conclusion, exposure to some types of music may induce prolonged survival of fully allogeneic cardiac allografts and generate CD4<sup>+</sup>
CD25<sup>+</sup>
Foxp3<sup>+</sup>
regulatory cells.</s0><fC02 i1="01" i2="X"><s0>002B25</s0>
</fC02><fC02 i1="02" i2="X"><s0>002A06F</s0>
</fC02><fC03 i1="01" i2="X" l="FRE"><s0>Homotransplantation</s0>
<s5>01</s5>
</fC03><fC03 i1="01" i2="X" l="ENG"><s0>Homotransplantation</s0>
<s5>01</s5>
</fC03><fC03 i1="01" i2="X" l="SPA"><s0>Homotrasplante</s0>
<s5>01</s5>
</fC03><fC03 i1="02" i2="X" l="FRE"><s0>Musique</s0>
<s5>02</s5>
</fC03><fC03 i1="02" i2="X" l="ENG"><s0>Music</s0>
<s5>02</s5>
</fC03><fC03 i1="02" i2="X" l="SPA"><s0>Música</s0>
<s5>02</s5>
</fC03><fC03 i1="03" i2="X" l="FRE"><s0>Exposition</s0>
<s5>03</s5>
</fC03><fC03 i1="03" i2="X" l="ENG"><s0>Exposure</s0>
<s5>03</s5>
</fC03><fC03 i1="03" i2="X" l="SPA"><s0>Exposición</s0>
<s5>03</s5>
</fC03><fC03 i1="04" i2="X" l="FRE"><s0>Coeur</s0>
<s5>05</s5>
</fC03><fC03 i1="04" i2="X" l="ENG"><s0>Heart</s0>
<s5>05</s5>
</fC03><fC03 i1="04" i2="X" l="SPA"><s0>Corazón</s0>
<s5>05</s5>
</fC03><fC03 i1="05" i2="X" l="FRE"><s0>Survie</s0>
<s5>06</s5>
</fC03><fC03 i1="05" i2="X" l="ENG"><s0>Survival</s0>
<s5>06</s5>
</fC03><fC03 i1="05" i2="X" l="SPA"><s0>Sobrevivencia</s0>
<s5>06</s5>
</fC03><fC03 i1="06" i2="X" l="FRE"><s0>Pronostic</s0>
<s5>08</s5>
</fC03><fC03 i1="06" i2="X" l="ENG"><s0>Prognosis</s0>
<s5>08</s5>
</fC03><fC03 i1="06" i2="X" l="SPA"><s0>Pronóstico</s0>
<s5>08</s5>
</fC03><fC03 i1="07" i2="X" l="FRE"><s0>Lymphocyte T</s0>
<s5>09</s5>
</fC03><fC03 i1="07" i2="X" l="ENG"><s0>T-Lymphocyte</s0>
<s5>09</s5>
</fC03><fC03 i1="07" i2="X" l="SPA"><s0>Linfocito T</s0>
<s5>09</s5>
</fC03><fC03 i1="08" i2="X" l="FRE"><s0>Animal</s0>
<s5>11</s5>
</fC03><fC03 i1="08" i2="X" l="ENG"><s0>Animal</s0>
<s5>11</s5>
</fC03><fC03 i1="08" i2="X" l="SPA"><s0>Animal</s0>
<s5>11</s5>
</fC03><fC03 i1="09" i2="X" l="FRE"><s0>Souris</s0>
<s5>12</s5>
</fC03><fC03 i1="09" i2="X" l="ENG"><s0>Mouse</s0>
<s5>12</s5>
</fC03><fC03 i1="09" i2="X" l="SPA"><s0>Ratón</s0>
<s5>12</s5>
</fC03><fC03 i1="10" i2="X" l="FRE"><s0>Médecine</s0>
<s5>17</s5>
</fC03><fC03 i1="10" i2="X" l="ENG"><s0>Medicine</s0>
<s5>17</s5>
</fC03><fC03 i1="10" i2="X" l="SPA"><s0>Medicina</s0>
<s5>17</s5>
</fC03><fC03 i1="11" i2="X" l="FRE"><s0>Transplantation</s0>
<s5>18</s5>
</fC03><fC03 i1="11" i2="X" l="ENG"><s0>Transplantation</s0>
<s5>18</s5>
</fC03><fC03 i1="11" i2="X" l="SPA"><s0>Trasplantación</s0>
<s5>18</s5>
</fC03><fC03 i1="12" i2="X" l="FRE"><s0>Greffe</s0>
<s5>25</s5>
</fC03><fC03 i1="12" i2="X" l="ENG"><s0>Graft</s0>
<s5>25</s5>
</fC03><fC03 i1="12" i2="X" l="SPA"><s0>Injerto</s0>
<s5>25</s5>
</fC03><fC03 i1="13" i2="X" l="FRE"><s0>Traitement</s0>
<s5>26</s5>
</fC03><fC03 i1="13" i2="X" l="ENG"><s0>Treatment</s0>
<s5>26</s5>
</fC03><fC03 i1="13" i2="X" l="SPA"><s0>Tratamiento</s0>
<s5>26</s5>
</fC03><fC03 i1="14" i2="X" l="FRE"><s0>Antigène CD4</s0>
<s4>INC</s4>
<s5>86</s5>
</fC03><fC03 i1="15" i2="X" l="FRE"><s0>Cellule régulatrice</s0>
<s4>CD</s4>
<s5>96</s5>
</fC03><fC03 i1="15" i2="X" l="ENG"><s0>Regulatory cell</s0>
<s4>CD</s4>
<s5>96</s5>
</fC03><fC07 i1="01" i2="X" l="FRE"><s0>Rodentia</s0>
<s2>NS</s2>
</fC07><fC07 i1="01" i2="X" l="ENG"><s0>Rodentia</s0>
<s2>NS</s2>
</fC07><fC07 i1="01" i2="X" l="SPA"><s0>Rodentia</s0>
<s2>NS</s2>
</fC07><fC07 i1="02" i2="X" l="FRE"><s0>Mammalia</s0>
<s2>NS</s2>
</fC07><fC07 i1="02" i2="X" l="ENG"><s0>Mammalia</s0>
<s2>NS</s2>
</fC07><fC07 i1="02" i2="X" l="SPA"><s0>Mammalia</s0>
<s2>NS</s2>
</fC07><fC07 i1="03" i2="X" l="FRE"><s0>Vertebrata</s0>
<s2>NS</s2>
</fC07><fC07 i1="03" i2="X" l="ENG"><s0>Vertebrata</s0>
<s2>NS</s2>
</fC07><fC07 i1="03" i2="X" l="SPA"><s0>Vertebrata</s0>
<s2>NS</s2>
</fC07><fC07 i1="04" i2="X" l="FRE"><s0>Chirurgie</s0>
<s5>37</s5>
</fC07><fC07 i1="04" i2="X" l="ENG"><s0>Surgery</s0>
<s5>37</s5>
</fC07><fC07 i1="04" i2="X" l="SPA"><s0>Cirugía</s0>
<s5>37</s5>
</fC07><fC07 i1="05" i2="X" l="FRE"><s0>Appareil circulatoire</s0>
<s5>38</s5>
</fC07><fC07 i1="05" i2="X" l="ENG"><s0>Circulatory system</s0>
<s5>38</s5>
</fC07><fC07 i1="05" i2="X" l="SPA"><s0>Aparato circulatorio</s0>
<s5>38</s5>
</fC07><fN21><s1>184</s1>
</fN21><fN44 i1="01"><s1>OTO</s1>
</fN44><fN82><s1>OTO</s1>
</fN82><pR><fA30 i1="01" i2="1" l="ENG"><s1>Congress of the Asian Society of Transplantation</s1>
<s2>12</s2>
<s3>Seoul KOR</s3>
<s4>2011-09-25</s4>
</fA30><server><NO>PASCAL 12-0238595 INIST</NO>
<ET>Music Exposure Induced Prolongation of Cardiac Allograft Survival and Generated Regulatory CD4<sup>+</sup>
Cells in Mice</ET><AU>UCHIYAMA (M.); JIN (X.); ZHANG (Q.); AMANO (A.); WATANABE (T.); NIIMI (M.); YU SEUN KIM; SU KIL PARK</AU>
<AF>Department of Cardiovascular Surgery , Juntendo University Hospital/Tokyo/Japon (1 aut., 4 aut.); Department of Surgery , Teikyo University/Tokyo/Japon (1 aut., 2 aut., 3 aut., 5 aut., 6 aut.); Department of Cardiovascular and Thoracic Surgery , The 4th Affiliated Hospital to Harbin Medical University/Harbin/Chine (2 aut.)</AF>
<DT>Publication en série; Congrès; Niveau analytique</DT>
<SO>Transplantation proceedings; ISSN 0041-1345; Coden TRPPA8; Pays-Bas; Da. 2012; Vol. 44; No. 4; Pp. 1076-1079; Bibl. 16 ref.</SO>
<LA>Anglais</LA>
<EA>In clinical practice, music has been used to decrease stress, heart rate, and blood pressure and to provide a distraction from disease symptoms. We investigated sound effects on alloimmune responses in murine heart transplantation. Naive and eardrum-ruptured CBA/N (CBA, H2<sup>K</sup>
) underwent transplantation of a C57BL/6 (B6, H2<sup>b</sup>
) heart and were exposed to 1 of 3 types of music-opera (La Traviata), classical (Mozart), and New Age (Enya)-or 1 of 6 different single sound frequencies for 7 days. An adoptive transfer study was performed to determine whether regulatory cells were generated in allograft recipients. Cell-proliferation, cytokine, and flow cytometry assessments were also performed. CBA recipients of a B6 graft exposed to opera and classical music had significantly prolonged allograft survival (median survival times [MSTs], 26.5 and 20 days, respectively), whereas those exposed to 6 single sound frequencies and New Age did not (MSTs, 7, 8, 9, 8, 8, 8, and 11 days, respectively). Untreated and eardrum-ruptured CBA rejected B6 grafts acutely (MSTs, 7 and 8.5 days, respectively). Adoptive transfer of whole splenocytes, CD4<sup>+</sup>
cells, and CD4<sup>+</sup>
CD25<sup>+</sup>
cells from opera-exposed primary recipients resulted in significantly prolonged allograft survival in naive secondary recipients (MSTs, 36, 68, and >50 days, respectively). Cell-proliferation, interleukin (IL)-2 and interferon-y were suppressed in opera-exposed mice, whereas IL-4 and IL-10 from opera-exposed recipients were up-regulated. Flow cytometry studies showed an increased CD4<sup>+</sup>
CD25<sup>+</sup>
Foxp3<sup>+</sup>
cell population in splenocytes from opera-exposed mice. In conclusion, exposure to some types of music may induce prolonged survival of fully allogeneic cardiac allografts and generate CD4<sup>+</sup>
CD25<sup>+</sup>
Foxp3<sup>+</sup>
regulatory cells.</EA><CC>002B25; 002A06F</CC>
<FD>Homotransplantation; Musique; Exposition; Coeur; Survie; Pronostic; Lymphocyte T; Animal; Souris; Médecine; Transplantation; Greffe; Traitement; Antigène CD4; Cellule régulatrice</FD>
<FG>Rodentia; Mammalia; Vertebrata; Chirurgie; Appareil circulatoire</FG>
<ED>Homotransplantation; Music; Exposure; Heart; Survival; Prognosis; T-Lymphocyte; Animal; Mouse; Medicine; Transplantation; Graft; Treatment; Regulatory cell</ED>
<EG>Rodentia; Mammalia; Vertebrata; Surgery; Circulatory system</EG>
<SD>Homotrasplante; Música; Exposición; Corazón; Sobrevivencia; Pronóstico; Linfocito T; Animal; Ratón; Medicina; Trasplantación; Injerto; Tratamiento</SD>
<LO>INIST-14765.354000506991730710</LO>
<ID>12-0238595</ID>
</server>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Musique/explor/MozartV1/Data/PascalFrancis/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000043 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Corpus/biblio.hfd -nk 000043 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Musique
|area= MozartV1
|flux= PascalFrancis
|étape= Corpus
|type= RBID
|clé= Pascal:12-0238595
|texte= Music Exposure Induced Prolongation of Cardiac Allograft Survival and Generated Regulatory CD4+ Cells in Mice
}}
| This area was generated with Dilib version V0.6.20.
Data generation: Sun Apr 10 15:06:14 2016. Site generation: Tue Feb 7 15:40:35 2023 |  |
